Epidemiological and risk assessment evidence of disease linked to HPC bacteria

7.1 INTRODUCTION Evidence proving that a particular microbe causes disease in humans is frequently difficult to obtain. For over a century, Koch's postulates have been accepted as being as close to proof as is likely to be achieved. If any microorganism satisfies these postulates, then most microbiologists would accept that the organism was indeed pathogenic. Koch's postulates are as follows: (1) The organism is regularly found in the lesions of the disease.